Ex parte CHARLTON et al. - Page 4




          Appeal No. 94-2504                                                           
          Application 07/963,676                                                       
               particularly point out and distinctly claim the subject                 
               matter which applicant regards as the invention.                        
                    The claims should all relate to the host of                        
               the tissue and not as claimed.                                          
                    Claims 1 and 11-16 are rejected under 35 U.S.C.                    
               § 112, first paragraph, as the disclosure is enabling                   
               only for claims limited in accord with the entire                       
               disclosure.  See M.P.E.P. §§ 706.03(n) and 703.03(z).                   
                    “A cell membrane permeant calcium buffer” is                       
               broader than the specific supporting disclosure.                        
               It is also broader than the elected invention.                          
               In response to these rejections (Paper No. 7, filed May                 
          5, 1993), applicants canceled Claims 2 and 4 and amended Claim               
          1 to specify the “host” and to further define the “calcium                   
          buffer” as a chelating agent having a K  within a designated                 
                                                  D                                    
          range.                                                                       
               In the FINAL office action mailed May 13, 1993 (Paper                   
          No. 8), the examiner responded to applicants’ amendment and                  
          arguments as follows:                                                        
                    Claims 1 and 10-16 remain examined.                                
                    Claims 1 and 11-16 remain rejected for the reasons                 
               of record under 35 U.S.C. 112, 1st paragraph.                           
                    The rejected phrase remains too broad and such is                  
               broader than the elected invention.                                     
                    THIS ACTION IS MADE FINAL.                                         
               Appellants filed NOTICE OF APPEAL August 13, 1993.                      

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