Ex parte CHARLTON et al. - Page 5




          Appeal No. 94-2504                                                           
          Application 07/963,676                                                       
          Apparently, Claim 10 was considered allowable in independent                 
          form, and Claims 3, 5-9 and 17-25 stood withdrawn from                       
          consideration by the examiner.                                               
          2.   Introduction                                                            
               Claims 1 and 11-16 stand finally rejected under 35 U.S.C.               


          § 112, first paragraph, because the phrase “‘cell membrane                   
          permeant calcium buffer’ is broader than the specific                        
          supporting disclosure . . . [and] also broader than the                      
          elected invention” (Paper No. 6, page 2).  All claims on                     
          appeal stand or fall (Appeal Brief (Br.), p. 3) with                         
          independent Claim 1.  Claim 1 on appeal reads:                               
                    1.   A method of reducing the damaging effect of                   
               an injury to cells in mammalian tissue of a host in                     
               vivo and treatment of epilepsy, said method comprising                  
               treating a host in need of such treatment with a non-                   
               toxic, damage-reducing effective amount of a cell                       
               membrane permeant calcium buffer which is a calcium                     
               ion chelating agent having a K  selected from the                       
                                              D                                        
                           -4         -8                                              
               range 1 x 10  to 1 x 10  Molar.                                         
               Appellants argued in their Appeal Brief (Br.) that the                  
          examiner had not adequately considered the specificity with                  
          which the “calcium buffer” utilized in the method claimed is                 
          described                                                                    
          (Br. 5-6, bridging para.) and submitted the Declarations of                  

                                        - 5 -                                          





Page:  Previous  1  2  3  4  5  6  7  8  9  10  11  12  13  14  Next 

Last modified: November 3, 2007