Appeal No. 1996-1080 Application No. 07/869,111 According to appellants, the invention is directed to a process for selectively methylating the 6-hydroxy position of erythromycin A, and intermediates useful in this process, which process does not involve the formation of quaternary salts at the 3'-dimethylamino position (Brief, pages 2-3). Claims 1 and 3 are illustrative of the subject matter on appeal and a copy of these claims is attached as an Appendix to this decision. The examiner has relied upon the following references as evidence of obviousness: Faubl et al. (Faubl) 4,640,910 Feb. 3, 1987 Watanabe et al. (Watanabe) 0 158 467 Oct. 16, 1985 (Published European Patent Application) Kirk-Othmer, Encyclopedia of Chemical Technology, 3rd ed., Vol. 20, pp. 964-65, John Wiley & Sons, 1982. Claims 1 and 2 stand rejected under 35 U.S.C. § 103 as unpatentable over Faubl in combination with Watanabe and Kirk- Othmer (Answer, page 2). Claim 3 stands rejected under 35 U.S.C. § 103 as unpatentable over Watanabe1 in combination 1The last digit is omitted from the citation of Watanabe on page 3 of the Answer. However, this is a harmless error since the entire prosecution of this application and parent application no. 07/094,888 recognize the correct citation of 2Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 NextLast modified: November 3, 2007