Appeal No. 1997-1987
Application No. 08/108,005
335, March 1990. Specification, at page 3, lines 4-5.
However, appellant has found that administering methionine and
betaine at doses of 6 g/day for 14 days was not able to
significantly increase MTHF and SAMe body fluid levels.
Specification, page 3, lines 6-8.
III. Representative claims
Claims 15, 17, 22, and 23 are illustrative of the subject
matter on appeal and read as follows:
22. A therapeutic method for treating neurological
affections [sic] selected from the group consisting of
subacute encephalitis associated with dementia and vacuolar
myelopathies comprising administering to a patient in need
thereof a therapeutically effective amount of at least one
member selected from the group consisting of S-adenosyl-
methionine salt, 5-methyltetrahydrofolic acid and 5-
formyltetrahydrofolic acid.
15. A therapeutic method according to claim 22, wherein
the S-adenosylmethionine is administered at doses ranging from
100 and 2000 mg/day.
17. A therapeutic method according to claim 22,
wherein 5-methyltetrahydrofolic acid or 5-
formyltetrahydrofolic acid is administered at doses ranging
from 20 and 200 mg/day.
23. A therapeutic method according to claim 22, wherein
the S-adenosyl-methionine salt is administered at the same
3
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