Appeal No. 1997-1987 Application No. 08/108,005 encephalitis is caused by an inflammatory state of the brain; in contrast, senile or presenile dementia caused by Alzheimer’s disease is characterized by diffuse cerebral cortical atrophy, and microscopically by the presence of argyrophil cells, loss of neurons, and neurofibrillary tangles. Monaco states that multiinfarctual dementia is generated by the presence in the brain of a series of infarcts (localized circumscribed areas of ischemic tissue necrosis, due to inadequate blood flow), and cannot be considered equivalent to dementia associated with encephalitis. 5. The examiner argues that “appellant’s encephalitis associated with dementia and of vacuolar myelopathies is inherently encompassed in the dementia of the reference, especially in the absence of evidence to the contrary.” Answer, page 4, lines 8-11. However, the examiner fails to provide a basis in fact or technical reasoning which would reasonably support the determination that encephalitis associated with dementia and vacuolar myelopathies are inherently disclosed by Le Grazie. See Ex parte Levy, 17 USPQ2d 1461, 1464 (Bd. Pat. App. & Inter. 1990), and cases cited therein. 7Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 NextLast modified: November 3, 2007