Ex parte LA GRECA - Page 5




          Appeal No. 1997-1987                                                        
          Application No. 08/108,005                                                  


          group consisting of subacute encephalitis associated with                   
          dementia and vacuolar myelopathies.  The method comprises                   
          administering to a patient in need thereof a therapeutically                
          effective amount of at least one member selected from the                   
          group consisting of S-adenosyl-methionine salt, 5-                          
          methyltetrahydrofolic acid and 5-formyltetrahydrofolic acid.                
               2.  Anticipation under 35 U.S.C. § 102 requires a prior                
          art reference to disclose each and every element set forth in               
          the claims.  See RCA Corp. v. Applied Digital Data System,                  
          Inc., 730 F.2d 1440, 1444, 221 USPQ 385, 388 (Fed. Cir. 1984).              
               3.  Le Grazie discloses a therapeutic method for treating              
          organic mental disorders, in particular senile and presenile                


          primary degenerative Alzheimer dementia and multiinfarctual                 
          dementia.  The method comprises orally administering a                      
          therapeu-tically effective amount of 5-methyl-tetrahydrofolic               
          acid or    5-formyl-tetrahydrofolic acid or a pharmaceutically              
          acceptable salt thereof in a controlled release form.  Le                   
          Grazie, col. 1, lines 11-21, col. 2, lines 7-46.  However, Le               
          Grazie does not disclose treating a patient afflicted with                  


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