Appeal No. 1997-1987
Application No. 08/108,005
time or at close intervals with 5-methyltetrahydrofolic acid
or with 5-formyltetrahydrofolic acid.
IV. References
The references relied on by the examiner are:
Le Grazie 5,059,595 Oct. 22, 1991
Surtees et al. (Surtees), “Central-nervous system
methyl-group metabolism in children with
neurological complications of HIV infection,” The
Lancet, vol. 335, pp. 619-621 (1990).
V. Rejections
The claims stand rejected as follows:
Claims 17, 18 and 22 under 35 U.S.C. § 102(e) as
anticipated by Le Grazie.
Claims 13 through 18 and 22 through 26 under 35 U.S.C. §
103 as unpatentable over the combined teachings of Le Grazie
and Surtees.
VI. Discussion
A. Rejection of claims 17, 18 and 22 under 35 U.S.C.
§ 102(e) as anticipated by Le Grazie.
1. The claimed subject matter is drawn to a therapeutic
method for treating neurological afflictions selected from the
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