Interference 103,482
that the average sequence length of the isotactic and
syndiotactic sequences to which Dolle’s claims refer may be
calculated in a manner inconsistent with Randall’s well known
teaching that the average sequence length is most accurately
calculated using a triad analysis of C-13 NMR pentad
distributions and formulas well known for use in calculating
average sequence length based on a triad analysis, especially
given Dolle’s reference examples providing pentad distribution
data based on C-13 NMR spectra and calculated n and niso syn
values with which to verify one’s calculations.
Therefore, contrary to Dr. Atwood’s opinion (RE 16-17),
we find that Dolle’s references to “an average length of
isotactic sequences” and “an average length of syndiotactic
sequences” have special meanings and that their special
meanings readily could have been determined from the
disclosure of Dolle Application 08/147,006. The average
sequence length values (n and n ) Dolle provides for theiso syn
polymers produced by the methods of his examples can only be
reproduced employing the accurate triad analysis of Dolle’s
pentad distribution data Randall describes and the formulas
persons skilled in the art, eg. Buschermohle, are known to
have utilized for calculating average sequence lengths based
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