BRAKE v. SINGH - Page 83




               Interference 102,728                                                                                                  
                       Singh, on the other hand, has not provided any testimony from Mr. Ng, the                                     
               scientist who synthesized the 24-mer, that he was aware of Dr. Singh’s intended use of                                
               the compound.  That is, Mr. Ng has not testified that he was aware that Dr. Singh was                                 
               going to use the 24-mer in the loop deletion mutagenesis procedure to synthesize a                                    
               compound within the scope of the count.  In fact, Singh has not pointed to one                                        
               declarant who has testified that Dr. Singh discussed his plan to employ the 24-mer in                                 
               the loop deletion mutagenesis procedure.  Burroughs v. Wellcome Co. v. Barr                                           
               Laboratories, Inc., 40 F.3d at 1228, 32 USPQ2d at 1919 (“The conception analysis                                      
               necessarily turns on the inventor’s ability to describe his invention with particularity.                             
               Until he can do so, he cannot prove possession of the complete mental picture of the                                  
               invention”).                                                                                                          
                       Thus, in Berges the Court found that a reasonable analysis of all the evidence                                
               established the existence of the compound of the count.  The Court’s holding of an                                    
               actual reduction to practice of the invention did not rest solely on the finding that the two                         
               reagents used to make the invention had no other substantial use except for the                                       
               research team’s stated goal.  Here, however, since Singh has only provided as                                         
               evidence of conception, the order of one of two reagents needed to perform the loop                                   
               deletion mutagenesis procedure, i.e., the 24-mer, but no evidence that the 24-mer                                     
               cannot be used for other procedures, we find the facts of this case insufficient to                                   
               substantiate the application of the Berges “no other substantial use” for a reagent rule.                             




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