Ex Parte EVANS et al - Page 2


                 Appeal No.  2001-2584                                                         Page 2                  
                 Application No.  08/462,817                                                                           

                 examiner.  Therefore, we remand the application to the examiner to consider the                       
                 following issues and take appropriate action.                                                         
                                                                                                                      
                        Claims 47 and 58 are illustrative of the subject matter on appeal and are                      
                 reproduced below:                                                                                     
                        47. A recombinant expression system for production of functional steroid                       
                             receptor protein(s), which comprises host cells containing exogenous                      
                             DNA encoding said protein(s), and wherein the DNA is operably                             
                             linked to control sequences compatible with said host cell.                               
                        58. A recombinant expression system for production of functional                               
                             members of steroid/thyroid hormone receptor superfamily of                                
                             protein(s), said system comprising host cells containing exogenous                        
                             nucleic acid encoding a protein having hormone binding and/or                             
                             transcription activating properties of a member of the steroid/thyroid                    
                             hormone receptor superfamily, wherein said exogenous nucleic acid                         
                             is operably linked to control sequences compatible with said host                         
                             cells.                                                                                    
                        Claim 49 depends from claim 48, which in turn depends from claim 47.                           
                 Claim 48 adds a further limitation wherein the host cells are mammalian, and                          
                 claim 49 further limits the mammalian host cells of claim 48 to CV-1 cells.  In                       
                 addition, claim 60 depends from claim 58 and adds the further limitation wherein                      
                 the host cells are CV-1 cells.                                                                        
                        The examiner relies upon the following reference:                                              
                 Green et al., (Green), “Human oestrogen receptor cDNA: sequence, expression                           
                 and homology to v-erb-A,” Nature, Vol. 320, pp. 134-139 (1986)                                        













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