Ex Parte EVANS et al - Page 10


                 Appeal No.  2001-2584                                                        Page 10                  
                 Application No.  08/462,817                                                                           
                 It appears, from this argument, that appellants’ are addressing the examiner’s                        
                 quotation from Clarke, explaining that in an appropriate case a single species                        
                 could be sufficient to antedate indirectly a different species of a reference.  See                   
                 Reply Brief, page 9, “[a]ppellants submit that one need not provide every species                     
                 of the claimed invention by way of a 37 CFR [sic] § 1.131 Declaration….”                              
                        With regard to the examiner’s second argument (Answer, page 10),                               
                 reproduced above, the examiner is attempting to shift his burden to appellants to                     
                 “explain how the reduction to practice of an isolated cDNA encoding a human                           
                 glucocorticoid receptor would have rendered obvious the isolated cDNA                                 
                 encoding the estrogen receptor of Green et al.”  Appellants, however, explain                         
                 (Brief, page 11) that the glucocorticoid receptor is a species within the genus of                    
                 receptor proteins set forth in appellants’ claimed invention, as is (as the examiner                  
                 has found) the estrogen receptor.  In our opinion, it is the examiner who has                         
                 failed to meet his burden, in the first instance, of establishing the facts necessary                 
                 to demonstrate that the evidence supplied by appellants is insufficient to                            
                 overcome the rejection.                                                                               
                        Accordingly, we vacate this rejection and remand the application to the                        
                 examiner to first determine whether each claim in the pending application is                          
                 supported by and thereby entitled to benefit of the filing date of appellants’                        
                 06/922,585 application.  After this determination is made, the examiner should                        
                 step back and consider the specification and prosecution history (including any                       
                 declarations provided by appellants), together with the relevant prior art.  If the                   
                 examiner believes that a rejection is necessary, the examiner should issue an                         






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