Ex Parte FRANCOIS et al - Page 6




          Appeal No. 2001-1335                                                        
          Application No. 08/843,582                                                  

          102 cannot be predicated on conjecture.  W.L. Gore & Assocs. v.             
          Garlock, Inc., 721 F.2d 1540, 1554, 220 USPQ 303, 314 (Fed. Cir.            
          1983); Ex parte Standish, 10 USPQ2d 1454, 1457 (Bd. Pat. App.               
          Int. 1988).  It follows that the section 102 rejection of claim             
          28 as being anticipated by Bringmann III cannot be sustained.               
               Regarding the section 103 rejections, we agree with the                
          appellants that the Bringmann I, Bringmann II and Bringmann IV              
          references contain no teaching or suggestion that the compounds             
          disclosed therein possess any kind of pharmaceutical activity               
          much less an antimalarial activity and therefore would not have             
          suggested a pharmaceutical composition which contains an                    
          antimalarially effective amount of at least one compound of the             
          types here under consideration as required by appealed claims 28-           
          33.  According to the examiner, “[s]ince it is known that all               
          these compounds (Bringmann I, II, IV) are natural products                  
          derived from plants traditionally used for treating malaria, it             
          is [sic, would have been] obvious for one of ordinary skill in              
          the art to identify, extract and purify the active ingredients              
          from the antimalarial plants and prepare the anti-malarial                  
          composition to arrive at the instant [i.e., the here claimed                
          composition]” (answer, page 9).  The examiner’s position is not             
          well taken for a number of reasons.                                         

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