Ex Parte FRANCOIS et al - Page 7




          Appeal No. 2001-1335                                                        
          Application No. 08/843,582                                                  

               First, the Bringmann I, Bringmann II and Bringmann IV                  
          references do not disclose that the compounds described therein             
          are derived from plants which are “traditionally used for                   
          treating malaria” (id.).  While other references such as                    
          Bringmann V and Ruangrungsi may contain such disclosure, these              
          references have not been applied against composition claims 28-             
          33.1  For this reason alone, the examiner’s position concerning,            
          and her concomitant rejection of, composition claims 28-33 are              
          without merit.                                                              
               Additionally, this position is unpersuasive with respect to            
          method claims 34-45 which have been rejected over references that           
          include Bringmann V and Ruangrungsi.  This is because a prima               
          facie case of obviousness is not established by the mere fact               
          that the compounds under consideration are derived from plants              

               1 We observe that Bringmann V and Ruangrungsi, like the                
          Bringmann I, Bringmann II and Bringmann IV references, disclose             
          compounds of the type defined by the appealed composition claims.           
          However, unlike the Bringmann I, Bringmann II and Bringmann IV              
          references, Bringmann V and Ruangrungsi also disclose that these            
          compounds are derived from plants used in folk medicine for                 
          treating, for example, malaria.  In light of these more                     
          comprehensive disclosures, it is unclear why the examiner did not           
          rely upon Bringmann V and Ruangrungsi (rather than Bringmann I,             
          Bringmann II and Bringmann IV) as primary references in her                 
          section 103 rejections.  While such reliance would not have                 
          resulted in sustainable rejections as discussed more fully in the           
          body of our decision, the examiner’s above quoted position would            
          have been, at least arguably, rational and germane with respect             
          to composition claims 28-33.                                                
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