Ex Parte FRANCOIS et al - Page 8




          Appeal No. 2001-1335                                                        
          Application No. 08/843,582                                                  

          used in folk medicine for treating, for example, malaria.  In               
          this regard, we point to the Boyd declaration under 37 CFR                  
          § 1.132 of record which evinces, inter alia, that “[t]he vast               
          majority of compounds isolated from plants purportedly used in              
          folk medicine do not exhibit the biological activity associated             
          with the medicinal application for which the plant is purportedly           
          used in folk medicine” and that, “[i]ndeed, the vast majority of            
          compounds isolated from plants, including plants purportedly used           
          in folk medicine, do not exhibit any biological activity                    
          whatsoever when subjected to biological screening” (item 8).                
          Particularly in view of this declaration evidence, it is apparent           
          that the examiner’s conclusion of obviousness is inappropriately            
          based upon an “obvious to try” standard which is not the proper             
          standard under section 103.  In re O’Farrell, 853 F.2d 894, 904,            
          7 USPQ2d 1673, 1681 (Fed. Cir. 1988).  Stated otherwise, the                
          prior art applied by the examiner, including the Bringmann V and            
          Ruangrungsi references, contain nothing which would have given an           
          artisan with ordinary skill a reasonable basis for expecting the            
          compounds under consideration would be successful for treating              
          malaria.  Id.                                                               
               Under these circumstances, we also cannot sustain the                  
          examiner’s section 103 rejection of claims 28-33 as being                   

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