Ex Parte Skinner et al - Page 4

               Appeal No. 2006-2710                                                                        
               Application No. 10/458,114                                                                  

               2.  OBVIOUSNESS                                                                             
                      Claim 1 stands rejected under 35 U.S.C. § 103 as obvious over                        
               Neumann1 in view of Snyder.2  The Examiner states that, “[a]t best, the                     
               claim differs from Neumann . . . in reciting use of a silane bonding agent.”                
               (Answer 3.)  The Examiner argues that it “would have been obvious to use a                  
               silane bonding agent in Neumann . . . because Snyder . . . discloses that                   
               siloxanes are the most useful and most widely available bonded phase                        
               chromatography packings and are hydrolytically stable.”  (Id.)                              
                      In particular, the Examiner argues that Neumann “is not particular as                
               to how the dendrimer is bonded to the substrate. . . .  A fair reading of . . .             
               Neumann . . . indicates that use of a triazine is one of many bonding                       
               methods and Neumann . . . is not limited to triazine.”  (Answer 3-4.)  In                   
               addition, the Examiner argues that Neumann “specifically indicates that the                 
               dendrimer could be first formed and then bonded to the substrate or built on                
               the substrate itself.”  (Answer 4 (citing Neumann, p. 4, l. 20, to p. 5, l. 4).)            
                      Furthermore, the Examiner argues that Neumann discloses that “the                    
               dendrimers are ‘functionalized by appropriate groups’ including ‘alkyl                      
               having 1-20 C atoms.’  As such, Neumann[]’s dendrimers are disclosed to be                  
               alkylated.  Alkylating a polymelamine dendrimer forms an alkylated amine                    
               functional macromolecule.”  (Answer 4-5 (citing Neumann, p. 3, ll. 32-34,                   
               and p. 9, claims 1-4).)                                                                     
                                                                                                          
               1 Neumann-Rodekirch et al., German Patent Publication No. DE 196 21 741                     
               A1, published December 4, 1997.  The citations are to the English-language                  
               translation of record.                                                                      
               2 Snyder, Introduction to Modern Liquid Chromatography 272-275 (John                        
               Wiley & Sons, Inc. 1979).                                                                   
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