Ex Parte Skinner et al - Page 7

               Appeal No. 2006-2710                                                                        
               Application No. 10/458,114                                                                  

               and, in addition, alkylates the dendrimers while bound to the solid                         
               substrate.”  (Br. 4.)  Appellants argue that the “Neumann process leads to                  
               materials that are randomly structured, are unstable, and [are] difficult to                
               manufacture.”  (Id.)                                                                        
                      Contrary to the arguments raised by Appellants, Neumann describes                    
               coupling a finished dendrimer to the stationary phase.  (Neumann 4.)  In                    
               addition, although “Neumann states that “a silica gel functionalized with                   
               -NH2 is particularly suitable for the use of poly(melamine)dendrimers” (id.),               
               Neumann does not require that the stationary phase be treated with an amino                 
               compound, or even that a triazine be used to bind the dendrimer to the                      
               stationary phase.  More importantly, Appellants have not demonstrated that                  
               the processes described in Neumann, modified to attach the dendrimer using                  
               an organosilane, would not result in the product recited in claim 1.  The                   
               “patentability of a claim to a product does not rest merely on a difference in              
               the method by which that product is made.  Rather, it is the product itself                 
               which must be new and unobvious.”  In re Pilkington, 411 F.2d 1345, 1348,                   
               162 USPQ 145, 147 (CCPA 1969) (emphasis in original).                                       
                      Appellants also argue that “the materials of the instant invention are               
               alkylated dendritic materials while the materials of Neumann are not.  Still                
               further, to arrive at the alkylated materials of this invention one has to treat            
               the bound dendritic materials with yet another step, which is not found in,                 
               nor suggested by Neumann, that is, a step for alkylation of the dendritic                   
               materials.”  (Br. 4.)  However, for the reasons discussed above, we conclude                
               that the Examiner has set forth a prima facie case that Neumann describes                   



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