Ex Parte Zasloff et al - Page 4


              Appeal No. 2007-0055                                                                 Page 4                
              Application No. 10/053,299                                                                                 

                     Claim 1 also uses another transitional phrase, “consisting essentially of,” stating                 
              that the claimed composition is “consisting essentially of an amino acid component”                        
              which is an isoleucine stereoisomer or active analog of it.                                                
                     “Consisting essentially of” is a transition phrase commonly used to signal a                        
                     partially open claim in a patent.  Typically, “consisting essentially of” precedes a                
                     list of ingredients in a composition claim or a series of steps in a process claim.                 
                     By using the term “consisting essentially of,” the drafter signals that the invention               
                     necessarily includes the listed ingredients and is open to unlisted ingredients that                
                     do not materially affect the basic and novel properties of the invention.                           
              PPG Industries Inc. v. Guardian Industries Corp., 156 F.3d 1351, 1354, 48 USPQ2d                           
              1351, 1353-54 (Fed. Cir. 1998).                                                                            
                     The specification defines the activity of the isoleucine compound as blocking the                   
              adherence of microbes to eukaryotic cells.  Specification, page 4, line 6-17.  This is also                
              expressly required by the claim which recites that the isoleucine is “present in a                         
              microbial blocking quantity.”  Accordingly, we understand this to be a “basic and novel”                   
              property of the claimed subject matter.  In this context, we construe the phrase                           
              “consisting essentially of” to permit additional unlisted ingredients (with the exception of               
              other amino acids) that do not affect the ability of the isoleucine compounds to block                     
              microbial adherence.                                                                                       
                     Claim 1 is a method of “blocking microbial adherence to a eukaryotic cell                           
              surface.”  However, it does not require that the “blocking” actually treat or prevent a                    
              disease associated with infection, or that any specific amount of blocking must be                         
              achieved by the claimed method.  Accordingly, we interpret the claim to cover any                          
              amount of blocking activity, including the blockade of one microbe from adhering to one                    
              cell.                                                                                                      





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