Ex Parte Zasloff et al - Page 15


              Appeal No. 2007-0055                                                               Page 15                 
              Application No. 10/053,299                                                                                 

              find no explanation in the record of how concentration (e.g., micrograms/ml) relates to                    
              quantity per square centimeter of cell surface area as recited in claims 2-4.  There is no                 
              information in the record before us of how to convert solution concentration as                            
              described in Zeng to the surface area units which are recited claims 2-4.  Consequently,                   
              we are unable to determine whether Zeng’s concentration of isoleucine overlaps with                        
              the quantity of isoleucine recited in the instant claims.  In sum, there is insufficient                   
              evidence of record to sustain this rejection.  We reverse the rejection of claims 2, 3, and                
              4.                                                                                                         
                     Claims 11-13 and 25                                                                                 
                     Claim 11 recites a composition comprising “from about 0.001 to about 99% by                         
              weight of an amino acid component” which is isoleucine or an active isoleucine analog,                     
              component B), and optionally component C).                                                                 
                     In regard to the amounts present in claim 11, Appellants argue that “[w]hether or                   
              not any isoleucine remains in the vagina after such neutralization is unknown and                          
              amounts to unfounded speculation.”  Brief, page 27.  We do not find this argument                          
              persuasive because the claim is to a composition, and does not require that isoleucine                     
              endure in the vagina for any length of time.  As discussed supra., p. 13 at fn.4, Zeng                     
              teaches a composition comprising 0.393% by weight of isoleucine.  This amount falls                        
              with the scope of claims 11, 12, and 13.  Accordingly, we affirm the rejection of these                    
              claims.  Claim 25 falls with claims 11-13 because it was not separately argued.                            










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