Ex Parte Zasloff et al - Page 12


              Appeal No. 2007-0055                                                               Page 12                 
              Application No. 10/053,299                                                                                 

              amounts disclosed by Zeng do not overlap with the claimed amounts because                                  
              “[w]hether or not any isolueicine [sic] remains in the vagina . . . is unknown and amounts                 
              to unfounded speculation.”  Id., 27.  Finally, they state that “[t]he discovery of optimum                 
              or workable ranges by routine experimentation for blocking cell surfaces using only                        
              isoleucine presupposes that Zeng knew about such a concept, which clearly he did not.”                     
              Id., 28.                                                                                                   
                     As was the case for the rejection over the Pederson patent, it is apparent that the                 
              Examiner’s basis for the rejection of claim 1 over Zeng is also grounded in inherency,                     
              i.e., that the amino acid composition disclosed in Zeng would inherently block microbial                   
              adherence as required by claim 1.  To determine the propriety of this rejection, we must                   
              determine whether there is reasonable basis to presume that Zeng’s composition                             
              achieves the goal stated in claim 1 of blocking microbial adherence.  Schreiber,                           
              128 F.3d at 1478, 44 USPQ2d at 1432.                                                                       
                     As we have construed claim 1, the phrase that the amino acid component is                           
              “selected from a group consisting of” isoleucine stereoisomers or active analogs of it                     
              limits the amino acid component to these compounds, excluding other amino acids.                           
              This claim construction differs from the construction given to the claims by the Examiner                  
              (Answer 20: § 2) which we find to be improper.  For this reason, we designate our                          
              rejection, which is described in more detail below, as a new ground of rejection. See                      
              37 CFR § 47.50 (b).                                                                                        
                     At column 4, lines 47-49, of Zeng, it is stated that “[t]he composition containing                  
              only one or two sodium salts of amino acids can also part[l]y realize the object of the                    
              invention.”  We find that this statement constitutes a description of a composition of                     




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