Ex Parte Zasloff et al - Page 8


              Appeal No. 2007-0055                                                                 Page 8                
              Application No. 10/053,299                                                                                 

              words in their ordinary usage as they would be understood by one of ordinary skill in the                  
              art, taking into account whatever enlightenment by way of definitions or otherwise that                    
              may be afforded by the written description contained in the applicant's specification.”                    
              In re Morris, 127 F.3d 1048, 1054, 44 USPQ2d 1023, 1027 (Fed. Cir. 1997); In re Crish,                     
              393 F.3d 1253, 1256, 73 USPQ2d 1364, 1367 (Fed. Cir. 2004).  An “analog” is defined                        
              as a compound which has a similar, but not identical structure to another.3  Pederson’s                    
              chelate comprises the isoleucine structure which is attached to a metal ion.  Pederson,                    
              column 3, lines 65-67.  This structure is similar, but not the same as isoleucine, and                     
              therefore we consider it to be an isoleucine analog that falls within the scope of the                     
              claim.                                                                                                     
                     Although Pederson’s chelate is an analog within the claim scope, there is no                        
              evidence of record that it would block microbial adherence as required by claim 1.                         
              Pederson shows that the amino (NH2) and carboxyl (COOH) groups of the amino acid                           
              are coordinated to the metal ion (M).  Pederson, column 6, lines 50-55.  There is no                       
              evidence in the record for presuming that this structure would still possess the claimed                   
              microbial blocking activity.  For this reason, we do not find that prima facie obviousness                 
              has been established for claim 1.  Accordingly, we reverse the rejection as it applies to                  
              claims 1-6, 8-10, 18, and 41-44.                                                                           
                     Claims 11-16, and 25                                                                                
                     Claim 11 is a composition claim, and does not require that the isoleucine                           
              component block microbial adherence to a eukaryotic cell surface in a mammal.  The                         
              composition comprises “A) from about 0.001 to about 99% by weight of an amino acid                         
                                                                                                                         
              3 Webster’s New Collegiate Dictionary 41 (1976)                                                            




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