VISSER et al v. HOFVANDER et al - Page 39




          Interference 103,579                                                        

               Helena Lab. Corp., 859 F.2d 878, 882, 8 USPQ2d 1468, 1472              
               (Fed. Cir. 1988). . . .                                                
                    When the meaning of a claim term is in doubt, we                  
               look to the specification for guidance.  See Hormone                   
          Research Foundation, Inc. v. Genentech, Inc., 904 F.2d                      
               1558, 1562, 15 USPQ2d 1039, 1042 (Fed. Cir. 1990) . . . .              
               Based on Claims 1 and 15 of Visser’s involved application,             
          we conclude that full length PGBSS cDNA or genomic DNA of                   
          Visser’s Claims 1 and 15 must code for PGBSS in its functional              
          [sense] orientation.  Visser’s method Claims 1 and 15 both                  
          utilize “at least one gene construct containing a full length               
          potato granule-bound starch synthase (PGBSS) cDNA or genomic DNA            
          sequence coding for PGBSS in reverse orientation in an expression           
          cassette which is functional in potato plants . . .” (emphasis              
          added).  These “gene construct[s] giv[e] . . . rise to tubers               
          containing amylose free starch” (Visser’s Claim 1).  The “full              
          length potato . . . GBSS . . . cDNA or genomic DNA sequence                 
          coding for PGBSS in reverse orientation” does not itself include            
          either the “upstream promoter base sequence” (Visser’s Claims 1             
          and 15) or “downstream transcription terminator base sequence”              


          (Visser’s Claims 1 and 15) which is necessary for the gene                  
          construct to give rise to tubers containing amylose free starch.            
          The “full length potato . . . GBSS . . . cDNA or genomic DNA                
          sequence coding for PGBSS in reverse orientation” is part of a              

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