Barton et al or Fischhoff et al v. Adang et al. - Page 99




          Interference 103,781                                                        

               Q.  And did you write down your concept of finding the                 
               poly-A sites and modifying the coding sequence to remove               
               them?                                                                  
               A.  Yes, we did.  We wrote this down.  Liz Murray wrote                
               it down in the notebook page and that’s the page I just                
               referred to.  But I also wrote it down in a draft of an                
               abstract that [sic, I] was preparing for a - the UCLA                  
               symposium talk.                                                        
               Q.  If you will look at Exhibit 125...                                 
               A.  Okay.                                                              
               Q.  And is this the abstract you’re referring to?                      
               A.  Yes, it is.                                                        
               Q.  And what is the date of this draft?                                
               A.  If we turn to the third page, the date of this abstract            
               is November 6th, 1985.                                                 
               Q.  And could you point specifically to where in this                  
               abstract you were referring to?                                        
               A.  I was referring to, on the second page of the abstract,            
               where it says, preliminary analysis of RNA indicates                   
               processing at internal sites in the toxin gene.  It                    
               appears that for efficient expression of this toxin in                 
               tobacco plants, the coding sequence must be modified                   
               to eliminate premature termination of transcription.                   
                    So I’m referring back to this - that we saw this                  
               chopped-up RNA and we knew it was polyadenylated.  And                 
               that we knew we needed to solve this problem and modify                
               the gene to eliminate these sites.                                     
               We are somewhat confused by Dr. Adang’s testimony.  He                 
          testified in Delaware I that Dr. Murray and he knew that the                
          chopped-up RNA fragments Dr. Murray reported at her laboratory              
          notebook page entitled “Bt Northerns,” dated October 22, 1985               

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