Ex parte SINGH et al. - Page 4




          Appeal No. 95-0865                                                           
          Application 08/08/007,950                                                    

               with the bis(2,3-protected hydroxymethyl)cyclobutane of the             
               formula                                                                 








               wherein:                                                                
                    a.   Prot is a hydroxy protecting group selected from              
                         the group consisting of                                       
                              (1) t-butyldimethylsilyl,                                
                              (2) t-butyldiphenylsilyl,                                
                              (3) (tri-phenylmethyl)dimethylsilyl,                     
                              (4) methyldiisopropylsilyl,                              
                              (5) triisopropylsilyl,                                   
                              (6) benzyl,                                              
                              (7) p-methoxybenzyl, and                                 
                              (8) acyl groups of the formula                           
                                                   O                                   
                                                   5                                   
                                              )))))C))R5                               
                                   wherein R  is                                       
                                             5                                         
                                        (a) straight or branched chain                 
                                              alkyl of 1 to 6 carbon atoms             
                                              or                                       
                                        (b) phenyl;                                    
                    b.   X is                                                          
                              (1) a perfluoroalkane sulfonyloxy group,                 

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