Interference 103,781 called electroporation that she and another scientist were developing for more rapid analysis of Bt genes in plant cells (AR 4156-4157; AR 6885). (17) Drs. Adang and Murray performed experiments directed towards transgenic expression systems based on constructions of a series of gene deletions of natural Bt genes (e.g., electroporation), associated with heli cell extracts, designed for heat shock promoters and constructs, and used to test Shaw Kamen sequences, “each of those experiments were for the purpose of identifying the gene part, region that needed or would benefit from fixing most . . . . Then we could go and rebuild the gene upon codon preference and codon frequency” (AR 0111-0112; AR 6884-6886). (18) Drs. Adang and Murray “had . . . some experiments on identifying destabilizing regions that . . . [they] were following up on up until . . . August, 1988" (AR 0114-0115). (19) “No,” Dr. Adang did not “believe that identifying the . . . destabilizing region would be necessary in order for . . . [the] invention involving increasing the number of plant-preferred codons in the native Bt gene to work” (AR 0116, l. 16-21). (20) Dr. Murray “thought the shorter RNA’s [identified by Northern blots] might have occurred due to some other -128-Page: Previous 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 NextLast modified: November 3, 2007