Barton et al or Fischhoff et al v. Adang et al. - Page 123




          Interference 103,781                                                        
                    . . . .  Moreover, I did not record every instance                
                    when I worked on the tables in my laboratory notebooks.           
                    On many days, which are not recorded, I spent a few               
                    hours entering sequence data into the computer for the            
                    codon usage tables.  Some of the codon usage tables               
                    are reflected in computer printouts . . . .  The                  
                    preparation of the codon usage tables was carried out             
                    without any significant gaps or delays.                           
                                                                                     
               Jan. 19-21, 1988 - Feb. 5, 1988: continued screening Bt                
                    constructs using electroporation (AR 6888, para. 12);             
               Feb. 5-26, 1988: analysis of Bt expression by Norther blots;           
                    planned upcoming Bt experiments; met with Ann Merlo to            
                    discuss future Bt experiments; and compiled codon usage           
                    tables (AR 6888, para. 13); and                                   
               Apr. 15, 1988 - June 13, 1988: maternity leave.                        
               In addition to the foregoing testimonial and documentary               
          evidence Adang specifically cites, Dr. Adang testified that the             
          collective evidence supports Adang’s position that it was first             
          to conceive of the invention of Claim 1 of its involved patent              
          corresponding to Count 2 and exercised reasonable diligence                 
          toward reduction to practice (AB 12, Fact 43).  However, Adang              
          cannot point to any evidence which explicitly describes the                 
          inventive concept defined by Claim 1 of Adang’s involved patent             
          corresponding to Count 2 (AR 4614, p. 1729, l. 3-20):                       
               Q.  . . . Now, Dr. Adang, when you came up with this idea              
               in the fall of 1985, did you write down this idea?                     
               A.  I have not found any documents that explicitly state               
               all this, the entire context of this idea.  What I have                
               found, and what we talked about here, is there is evidence             
               saying that we knew the Bt RNA was truncated.  We knew the             
               Bt gene was AT-rich.  We knew that the Bt genes preferred              
               AT codons.  We knew we were getting some type of termination           
                                        -123-                                         





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