Ex parte SINGH et al. - Page 16




          Appeal No. 95-0865                                                           
          Application 08/08/007,950                                                    

                     6                                         6                   
          referring R  in Method C; and page 10, lines 2-3 where R  is                 
          defined inter alia as hydrogen].                                             
                    31. The X  of Hagberg I Compound XIII is defined as2                                                        
          (page 13, lines 16-19):                                                      
               a leaving group such as chlorine (sic-chloro), bromine                  
               (sic-bromo), iodine (sic-iodo) or a group ) SO R  where R  is2 2       2               
               defined in Method B ***.                                                
          According to Method B (page 9, lines 21-24):                                 
               R  is alkyl containing 1-8 carbon atoms, fluorinated alkyl2                                                                      
               containing 1-8 carbon atoms such as trifluoromethyl,                    
               alkylaryl such as benzyl, or aryl such as unsubstituted or              
               substituted phenyl.                                                     
                               2                                  2      2           
                    32. When X  of Hagberg I Compound XIII is )  SO R  and R           
                                                                   2                   
          is trifluoromethyl, the Compound XIII leaving group is the same              
          as one of the leaving groups described by Bisacchi (X is triflyl)            
          (col. 3, lines 66-67).                                                       
                               2                                  2      2           
                    33. When X  of Hagberg I Compound XIII is )  SO R  and R           
                                                                   2                   
          is methyl (an alkyl having 1-8 carbon atoms), the Hagberg I                  
          Compound XIII leaving group is the same as one of the leaving                
          groups described by Bisacchi (X is mesyl) (col. 3, lines 64-65).             
                          1      12                                                    
                    34. R  and R  of Hagberg I Compound XIII may be alkyl              
          (e.g., methyl) [page 16, lines 9-10, referring to Method A and               


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