Appeal No. 95-0865
Application 08/08/007,950
(a) chloro, bromo, iodo,
(b) an aryl sulfonyloxy group,
(c) a substituted alkyl sulfonyloxy group,
(d) a nitro-substituted benzene sulfonyloxy group, and
(e) fluorosulfonyloxy, and
(2) "P" or "Prot" is a protecting group (Z ) selected from
1
the group consisting of:
(a) t-butyldimethylsilyl,
(b) t-butyldiphenylsilyl,
(c) (tri-phenylmethyl)dimethylsilyl,
(d) methyldiisopropylsilyl,
(e) triisopropylsilyl,
(f) benzyl,
(g) p-methoxybenzyl,
(h) trityl,
(i) 4-monomethoxytrityl,
(j) 4,4'-dimethoxytrityl and
(k) acyl groups of the formula
O
5
)))))C)) R5
wherein R is
5
i) straight or branched chain alkyl
of 1 to 6 carbon atoms or
ii) phenyl.
Slusarchyk differs from the invention defined by claim 25 in
that Slusarchyk does not describe the use of the purine in its
tetraalkylammonium salt form. Rather, Slusarchyk describes the
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